My guess is it will be something like New Vegas where your skills stats don't make or break you, but you will make choices that can limit which factions you can work with and which try and kill you on sight. I really don't see them going back to the Morrowind days where you progress with a faction would come to a dead stop based on your stats or something like that. I would love that though, but I ain't expecting it. At the very least I hope we can get rid of someone who has never cast a spell being the head of the mages guild like stuff but I also imagine it is a tough sell to get the higher-ups to agree to gate content behind stuff like "only mages will ever see this."