Someone will always go first but you can mitigate it a bit, like in Hearthstone with the coin.
I remember someone calculated going second in Gwent was worth around 6 or 7 points. Not something that can't be overcome but still an advantage. I don't even care too much about that advantage, it's the difference in how you have to play if you go first or second that annoys me. Going first is just never fun, having to make sure whatever card you play puts you ahead of the opponent, making it much more tempo based because you don't want to go two cards down. Whereas the person who goes second can just chill and bully the opponent, can always react to the opponents play etc. All of this is exasperated when there's carryover onboard.
