I mean yeah, but the canon EU has been pretty careful about that so far. We don't know what happened to Cal Kestis, so I'll ignore him for now, but Ezra was specifically plopped out of the timeline shortly before the battle of Yavin (by having the Purgill lead him and Thrawn into the unknown regions) and Ahsoka went on a journey in the force through the World Between Worlds and we don't know where or what her involvement really was.
Either way, I feel it was established that the only one who could have beaten Vader and Palpatine was Luke, due to his connection with Vader allowing Vader to return to the light, so Luke's arc in my opinion is still held up strong
All we know is Ahsoka is now looking for Thrawn and that definitely should mean Ezra is alive