The UI needs a bit work, took me a few days to finally get it exactly the way I want it.
They really need to figure out how to seperate looting and picking up weapons better. Why not use a differernt button for looting, so many things in this game requires you to hold the square button it's almost garanteed that you'll accidentally do the wrong thing multiple times in your playthrough.
Otherwise the game is great, I am loving every minute of it. Definitely the best Far Cry since 3, hell it's probably as good as 3.
I recommend playing on hard with no aim-assit, driving assit or any form of assit, gps off, vehicle hints off and all (skill/challenge etc.) notifications off. All that information are avalible to you in the pause screen, you don't need that shit bothering you while you are playing.
Trust me, once you "de-Ubisoft" the HUD the game become crazy immersive and absorbing.
I would even go as far as to say that if all reviewers played Far Cry 5 in this set up the game will recieve much better scores period.