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astroturfing

Member
Nov 1, 2017
6,466
Suomi Finland
if this spreads to the hospital i work at, i'll probably just quit. we are not equipped to deal with shit like this, too many people here don't even grasp the importance of disinfecting your hands between patients..

also dying from a bloodstream infection is probably one of the worst ways to die. i almost did and it was just incredibly hellish, like slow motion torture. pumped so full of drugs that i hallucinated for days and days in the ICU, experiencing all the worst nightmares my subconscious could come up with.
 

Deleted member 3812

User requested account closure
Banned
Oct 25, 2017
8,821
Yeaaaaaah was reading about this yesterday. That case where they found the fungus all over the room after quarantining it is nightmareish

Heres the CDC page:
https://www.cdc.gov/fungal/candida-auris/candida-auris-qanda.html

And here are the current Maps Comrade Doggo Sparky if you want to add to OP:
x6wBFPw.png



6dV6qyV.png

Oh fuck!!! My state of Maryland has a color and I was in a hospital ER this past weekend.....
 

Deleted member 3812

User requested account closure
Banned
Oct 25, 2017
8,821
This is really scary, CDC reports that this fungus can live on surfaces for several weeks: https://www.cdc.gov/fungal/candida-auris/c-auris-drug-resistant.html

Why is Candida auris a problem?
  • It causes serious infections. C. auris can cause bloodstream infections and even death, particularly in hospital and nursing home patients with serious medical problems. More than 1 in 3 patients with invasive C. auris infection (for example, an infection that affects the blood, heart, or brain) die.
  • It's often resistant to medicines. Antifungal medicines commonly used to treat Candida infections often don't work for Candida auris. Some C. auris infections have been resistant to all three types of antifungal medicines.
  • It's becoming more common. Although C. auris was just discovered in 2009, it has spread quickly and caused infections in more than a dozen countries.
  • It's difficult to identify. C. auris can be misidentified as other types of fungi unless specialized laboratory technology is used. This misidentification might lead to a patient getting the wrong treatment.
  • It can spread in hospitals and nursing homes. C. auris has caused outbreaks in healthcare facilities and can spread through contact with affected patients and contaminated surfaces or equipment. Good hand hygiene and cleaning in healthcare facilities is important because C. auris can live on surfaces for several weeks.
 

Zed

Member
Oct 28, 2017
2,544
It seems like the worst case scenario for this is that it basically infects most of the population (since it seems extremely resilient to disinfecting and seems to be growing on all kinds of surfaces) but it remains latent and then when people get immunocompromised it starts working. Say bye bye to relatively safe modern relative surgery since bodies will be wide open to being attacked by the fungus then.
 

Temp_User

Member
Oct 30, 2017
4,707
Welp. Better hope i dont get a flu or surgery or anything that taxes my immune system in the next few years until they get a proper anti-fungal against this thing.
 

Deleted member 3812

User requested account closure
Banned
Oct 25, 2017
8,821
According to Wikipedia, it sounds like this fungus will be very difficult to find a treatment for as there are "substantial genomic diversity" for this fungus and it was only discovered in 2009: https://en.wikipedia.org/wiki/Candida_auris

Geographical differentiation
The phylogenetics of C. auris suggest distinct genotypes exist in different geographical regions with substantial genomic diversity.[12] A variety of sequence-based analytical methods have been used to support this finding.

Whole genome sequencing and analyses of isolates from Pakistan, India, South Africa, Venezuela, Japan, and previously sequenced C. auris genomes deposited in the National Center for Biotechnology Information's Sequence Read Archive [13] identified a distinct geographic distribution of genotypes.[7] Four distinct clades separated by tens of thousands of single-nucleotide polymorphisms were identified.[7] The distribution of these clades segregated geographically to South Asia (India and Pakistan), South Africa, Venezuela, and Japan with minimal observed intraregion genetic diversity.[7]

Amplified fragment length polymorphism analysis of C. auris isolates from the United Kingdom, India, Japan, South Africa, South Korea, and Venezuela suggested that the London isolates formed a distinct cluster compared to the others.[14]

Comparison of ribosomal DNA sequences of C. auris isolates from Israel, Asia, South Africa, and Kuwait found that the strains from Israel were phylogenetically distinct from those from the other regions.[15] Chatterjee et al. wrote in 2015, "Its actual global distribution remains obscure as the current commercial methods of clinical diagnosis misidentify it as C. haemulonii."[5]

The Wikipedia article also states that this fungus is easily misidentified as other fungal species:

C. auris can cause invasive candidiasis (fungemia) in which the bloodstream, the central nervous system, and internal organs are infected. It has recently attracted increased attention because of its multiple drug resistance. Treatment is also complicated because it is easily misidentified as other Candida species.
 

Deleted member 3812

User requested account closure
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Oct 25, 2017
8,821
NY TImes reports that outbreaks of this fungus was either downplayed or kept confidential!!!!!: https://www.nytimes.com/2019/04/06/...tion=click&module=RelatedLinks&pgtype=Article

Why haven't people heard about this?

The rise of C. auris has been little publicized in part because it is so new. But also, outbreaks have at times been played down or kept confidential by hospitals, doctors, even governments. Some hospitals and medical professionals argue that because precautions are taken to prevent the spread, publicizing an outbreak would scare people unnecessarily.
 

Deleted member 3812

User requested account closure
Banned
Oct 25, 2017
8,821
Welp. Better hope i dont get a flu or surgery or anything that taxes my immune system in the next few years until they get a proper anti-fungal against this thing.

It might be very difficult to develop a drug to treat this new fungus: https://en.wikipedia.org/wiki/Candida_auris

The C. auris genome was found to encode several genes for the ABC transporter family, a major facilitator superfamily, which helps to explain its multiple drug resistance.[5] Its genome also encodes virulence-related gene families such as lipases, oligopeptide transporters, mannosyl transferases and transcription factors which facilitate colonization, invasion, and iron acquisition.[5] Another factor contributing to antifungal resistance is the presence of a set of genes known to be involved in biofilm formation.[5]
 

Deleted member 3812

User requested account closure
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Oct 25, 2017
8,821
The symptoms for being infected with this fungus could cause a person to think they have something else: https://www.nytimes.com/2019/04/06/...tion=click&module=RelatedLinks&pgtype=Article

Can I do anything to protect myself?
The symptoms of C. auris — fever, aches, fatigue — are not unusual, so it is hard to recognize the infection without testing. The good news is that the threat of becoming sick with C. auris is very low for healthy people going about their daily lives. If you or a loved one is in a hospital or nursing home, you can ask if there have been cases of Candida auris there. If so, it is reasonable to request that proper "infection control" precautions are taken.
 

iamaustrian

Member
Nov 27, 2017
1,291
This is quite a virulent strain (from the NYtimes article):

Thats not uncommon though.
If you find a tiny spot of mold in i.e. your bathroom there is a very high chance its spores have spread in your entire apartment.

Fungi spores (some bad, some not) are basicly everywhere all the time anyway.

I'm sure you heard the term "valley fever" before.
It's a fungural infection caused by spores found in super dry soil like desert sands (!) and dust in the south west of the US.

We had a pretty interesting class in psychology at the university about that fungus as it can also possibly invade your brain causing psychosis-like misbehavior.
 

Ginta

Banned
Oct 29, 2017
1,141
Yes Trump build the wall so it can't spread out of your country. /s

Hope they get it somehow under control. The population needs to be educated on that right now, otherwise it might be the biggest crisis the us has faced in a long time.
 

Deleted member 3812

User requested account closure
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Oct 25, 2017
8,821
Jeeze, the laboratory test for this fungus takes 1 to 2 weeks to get the resulta: https://www.cdc.gov/fungal/candida-auris/fact-sheets/c-auris-testing.html

Candida auris (also called C. auris) is a fungus that can cause serious infections. C. auris can spread from one patient to another in hospitals and nursing homes. Patients can carry C. auris somewhere on their body, even if it is not making them sick. This is called colonization. When people in hospitals and nursing homes are colonized, C. auris can spread from their bodies and can get on other people or nearby objects, allowing the fungus to spread to people around them.

CDC recommends testing patients who may have come in contact with C. auris to see if they are carrying this fungus. This allows healthcare providers to know who is carrying the fungus and take steps to prevent it from spreading to other people.

What should I expect if I get tested?

  1. The nurse or doctor will wipe or rub a cotton swab on the skin near your armpits and the area where your leg joins your body (groin). The test is not painful.
  2. The swab will be sent to a lab, and in 1 to 2 weeks, the lab will tell your doctor the results.
  3. If the test shows you are carrying the fungus, then your nurse or doctor will talk to you about the results and what to do next.
 

Bebpo

Member
Feb 4, 2018
4,640
As someone whose immune compromised and recently been dating a nurse who works in a nursing home in one of the states with a moderate number of infections of this, this is definitely a little concerning :/
 

Ocean Bones

Avenger
Oct 29, 2017
4,728
Terrifying! Hope they get a handle on it. Sounds like it could be a real nightmare for hospitals and nursing homes. If it gets really out of control.. Fuck.
 

ClickyCal'

Member
Oct 25, 2017
59,699
I was supposed to go to my neurologist later in the morning, that's technically in part of a hospital. I just have to go through a lobby part to get to the elevator to where they are. Should I not go?
 

donkey

Sumo Digital Dev
Verified
Oct 24, 2017
4,868
Well, time to cancel my visit to Chicago for my cousin's wedding.

Y'all stay safe!

EDIT: /s
 
Last edited:

iamaustrian

Member
Nov 27, 2017
1,291
I was supposed to go to my neurologist later in the morning, that's technically in part of a hospital. I just have to go through a lobby part to get to the elevator to where they are. Should I not go?

Well, time to cancel my visit to Chicago for my cousin's wedding.

Y'all stay safe!

I just can't tell if you are serious or not.

I mean, would you really cancel a doctors appointment or even a wedding because of rare infection which basicly only affects a handful of preconditioned patients?

would are you doing during a (real) flu epidemic which is also potentially deadly? lock yourself in for 2 months straight?
 

Lant_War

Classic Anus Game
Banned
Jul 14, 2018
23,601
As if climate change wasn't enough to be concerned with, the threat of drug-resisting bacteria AND fungus starts getting more serious. Fuck me, I wish I was born 50 years earlier. Even being black.



Literally the same thing with climate change. We knew everything 30+ years ago, yet in that timespan we've not only ignored the warnings mostly, we're polluting more than at any time in human history. Every year. Since before probably the majority of this board was alive. Oil and gas companies knew even earlier than the public too but C.R.E.A.M.

I don't know what the future will write about in regards to that time period between 1980 and the present + several years, but we define the whole cutting off the nose to spite the face thing.
Yeah future generations are going to be pissed at us.
 

JJH

Banned
Oct 27, 2017
2,881
I live in Illinois, work in a hospital in outpatient surgery. What do I win?
 

donkey

Sumo Digital Dev
Verified
Oct 24, 2017
4,868
I just can't tell if you are serious or not.

I mean, would you really cancel a doctors appointment or even a wedding because of rare infection which basicly only affects a handful of preconditioned patients?

would are you doing during a (real) flu epidemic which is also potentially deadly? lock yourself in for 2 months straight?
Thought the "stay safe" would've been enough without the /s
 

sgtnosboss

Member
Nov 9, 2017
4,786
Does the abuse of antibiotics that creates resistances affect antifungals at all?

Should add that it's good we just got a dem governor especially after Rauner's fuck up with sterigenics
There are different theories as to what happened with C. auris. Dr. Meis, the Dutch researcher, said he believed that drug-resistant fungi were developing thanks to heavy use of fungicides on crops.

Dr. Meis became intrigued by resistant fungi when he heard about the case of a 63-year-old patient in the Netherlands who died in 2005 from a fungus called Aspergillus. It proved resistant to a front-line antifungal treatment called itraconazole. That drug is a virtual copy of the azole pesticides that are used to dust crops the world over and account for more than one-third of all fungicide sales.

A 2013 paper in Plos Pathogens said that it appeared to be no coincidence that drug-resistant Aspergillus was showing up in the environment where the azole fungicides were used. The fungus appeared in 12 percent of Dutch soil samples, for example, but also in "flower beds, compost, leaves, plant seeds, soil samples of tea gardens, paddy fields, hospital surroundings, and aerial samples of hospitals."

Dr. Meis visited the C.D.C. last summer to share research and theorize that the same thing is happening with C. auris, which is also found in the soil: Azoles have created an environment so hostile that the fungi are evolving, with resistant strains surviving.

This is similar to concerns that resistant bacteria are growing because of excessive use of antibiotics in livestock for health and growth promotion. As with antibiotics in farm animals, azoles are used widely on crops.

"On everything — potatoes, beans, wheat, anything you can think of, tomatoes, onions," said Dr. Rhodes, the infectious disease specialist who worked on the London outbreak. "We are driving this with the use of antifungicides on crops."
https://www.nytimes.com/2019/04/06/health/drug-resistant-candida-auris.html
 
Oct 28, 2017
2,712
Siloam Springs
An insidious thought crossed my mind right now- Given the innate compulsion that your 45th Twisident has for lying, what are the chances that in the near future, if this issue grows further, he openly blames "illegal immigrants, asylum seekers etc" for as "potential carriers" of this disease during one of his re-election campaign rallies?

It would not be the first time that this idea, whilst not by Trump himself, has been floated openly on mainstream news during (IIRC) 2016 as part of an interview.

That's the obvious response to anything bad from T-45.