Class variety and build variety within classes is structured much more like Diablo, and seems to have much more depth than other loot shooters. The game is more ability-focused than gun-focused unlike Destiny and Division. The loot can actually affect your class abilities significantly. The game is structured around global difficulties rather than having a small subset of content for high level players to grind and making the low level content useless.
Those are off the top of my head.
class and builds arent loot. abilities arent loot. loot's effect on abilities being more significant than division and destiny would make it closer to Diablo sure, also not that hard to acheive. global difficulties also not loot.
Diablo loot is excessive, quick, and lots of stats with ranges and re-rolling and you're equipping loot while playing the content that's dropping that loot.
Anthem looks to be mission structured, make your loadout, do the thing, look at what you got, adjust loadout , choose another activity. the drops them selves seem sparse but builds and min maxing still the focus of the loot. the loot is also geometric shapes much like destiny.
i just see 2 very different loot systems with some similarities and i'm worried people are going to expect diablo like loot drops that litter the floor when from what i've seen drops are more like destiny but more varied stats that have more of an affect on gameplay and builds but that you can't see until missions end.