It's hard to have a proper discussion when the title and OP have framed it as Most Definitely Transphobic.
That may be the case.
My first post in this thread was that while it may not have been intended as transphobic (or anti LGBT in general really) that the artist should have had the foresight to craft the imagery in a way that didn't allow a bunch of coincidences to coalesce into something that could be misconstrued as such. It is unreasonable for someone to expect people to look into the history of an artist in order to understand a stand alone piece. I am criticizing this comic because it was poorly made if a pro-LGBT figure could accidentally make something that at first glance looked anti-LGBT.
I was accused of being upset and not understanding context.
So perhaps proper discussion was futile from the get go.