That's like asking a Zelda fan do they want to keep doing dungeons and puzzles forever, or Final Fantasy fan do they want to keep seeing summons and Molboro's; With most long time fans that enjoy and were drawn into those games because of those types of staples, you'll get a resounding yes and it's no different for me with Resident Evil.
RE didn't become my favorite game series back then because of over the top action, vampires or werewolfs; I fell in love with it because of it's bio-horror/science gone wrong themes, foreboding atmospheres/locations, and fun plots involving conspiracies/evil corporations, and I'm sure it's the same for lots of classic RE fans. New things/experimenting isn't the problem, since every classic entry after the original (up to 4) added new stuff that kept it fresh, but still kept the heart of the original (And the recent RE2 remake proved that formula is still viable with modern updates).
But the problem with RE is that it's gradually been losing it's original identity since RE4, and it's a problem that's has gone from a snowball to an avalanche, now with RE8. If I saw the RE8 trailer with no knowledge and didn't see Chris Redfield (and maybe the 1/2 second flash of an Umbrella symbol), I'd honestly have thought it was just a completely unrelated game, and that sums up the problem in and of itself.
So, in the most long-winded way possible, yes, if it meant moving in this direction, I'd rather take shooting zombies forever and beyond.