I don't think it'll reach N.Sane levels. I feel like there are fewer people who have played any or all 3 Spyro games so curiosity will definitely be an initial benefit to it, but I fear without some drivel like "tHe DaRk SoULs oF pLaTfOmErS" to latch on to, not being the first big remake like this, and being a pretty chill, casual experience it may not get the power of word of mouth that N.Sane garnered. Its platform spread may also hurt it a bit since Crash eventually made it to other consoles so PC/Switch people may wait it out.
Still, I think it will definitely end up successful. Even if Crash is more recognizable and successful Spyro fills a different and relatively more empty niche at the moment, which on top of its inherent qualities and good buzz will do well for it in the long run.
And considering how complimentary and joined at the hip the two franchises have always been I wonder if a proper Crash/Spyro crossover could be in the cards down the line.