I have had this issue. I sent my SX in, and they reset everything, and it still happened. What changed it for me was a new C1. I had a blue vertical line showing on my C1, so I had to exchange it. Once I got my new C1, I have not had this problem. I got the TV when it was first released. My new C1 has a build date of November 21.
The main problem is a faulty handshake somewhere. I changed cables, only to be left with the same issue. The flickering in my case was 100% of the time, and occasionally, I'll receive an "Unsupported Format" message from my panel when watching YouTube TV or YouTube. When this message was seen, I had to turn off the TV or console.
Here is what I think is happening. I believe there is an EDID read failure happening from the OS side. I believe it is an EDID read failure due to circumstances that follow the failure. For instance, when the failure occurs, often, the console will fall back to 640x480. From my experience, this is due to the OS failing to read the EDID correctly, and the GPU resorts to 640x480 to project an image despite the read failure. Also, when this failure happens, you cannot change the resolution, which indicates a read failure.
In the image below, none of the 4k settings are checked in the console's menu, so this could mean that none of the panel's information was passed to the console to set the modes correctly. If settings aren't displayed correctly, that means the system could not read the EDID to know what settings it supports.
Since I changed C1's, I have not had an issue. I'm using the same cable setup that was initially failing. I'm not entirely sure what changes, if any, went into the new C1's. I'm sure they are using the same TCON, but some slight modifications could have happened.