Not until GTA V revenues slow significantly. Sure, it only sold 20 million copies in 2020, but Take-Two is enjoying the recurring in-game sales of a F2P...but unlike Epic charges retail for the privilege. Full market saturation is the beginning of the harvest under this model and the mere announcement of a new GTA immediately places hundreds of millions of dollars from in-game revenue at risk. Frankly, we may never see a new GTA.
We've already heard from insiders with good track records that GTA is in development and has been for a few years.