Well AC2 and Brotherhood I have played, but I think Forgotten Sands Wii is significantly better. It has very imaginative level / puzzle design, using the Wii Remote really well. Probably one of the greatest surprise hits I have ever played.That one I never played, but I'm skeptical that it could be better than AC2 or Brotherhood.
Remember Max Design and Sunflowers though.Anyone not saying Anno is a cop! Just kidding, mine is easily Assassin's Creed <3