Structurally, my hope is that we get an X-Man movie every other year or so, with regular TV shows in-between. Solo Wolverine, Solo Storm, Cyclops & Jean, Rogue & Gambit, that sort of thing.
For the series itself, I honestly like the original Fox X-Men set-up - the core team already exists, already knows each other, they've been working as a team for years. Then you bring in an outsider as the audience introduction point. And I want that school absolutely packed, like 20-30 named characters that are essentially just background roles.
Like, just spitballing:
X-Men - Cyclops, Jean, Iceman, Nightcrawler, Storm, Rogue
Interim Series: Wolverine, Storm
Uncanny X-Men - Cyclops, Jean, Nightcrawler, Rogue, Wolverine
Interim Series: Rogue & Gambit, Kitty Pryde
Astonishing X-Men - Wolverine, Nightcrawler, Storm Rogue, Gambit, Kitty
Interim Series: Cyclops & Jean, Magneto
So you have character weaving in and out of the core team, when they retire or quit or whatever. You can have a "X-Men school drama" show with Kitty, then have her graduate to team member for the next movie. You have Rogue go AWOL in one movie, meet up with Gambit in a miniseries, then bring him back for the next movie. X-Men is their best chance to use their multimedia approach to the fullest, because there's way too many iconic characters to limit them to a new movie here and there.