Well if I just scoot on over to Smallville's wiki page...Gotta wonder if in Smallville's universe - are Lex and Clark friends again? Would that play a role?
After he had grafted his many clones' best pieces together to create his composite clone LX-Ø to which he was restored into thanks to an alternate-reality Lionel Luthor's deal with Darkseid, Lex met with Clark to look forward to their destiny together as arch-nemeses. He then mortally stabbed his half-sister Tess Mercer, who erased all of his memories using a neurotoxin
Due to the loss of his memories, Lex distrusts and hates Superman, seeing him as a potential threat to Earth. He has fulfilled his destiny as Superman's greatest enemy.
...gonna say probably not