Little update on this issue I was experiencing in case it might help someone else. So I bought a custom build from cyber power, gpu died after 2 days. Rma'd it, they replaced the video card and sent it back. As soon as I hooked it up, even the mildest static discharge (like you don't even feel a zap) could disconnect and reconnect the mouse from across the room. If I stood up from my couch and touched the mouse and made even the slightest zap, I could disconnect the mouse 100 percent of the time. Keyboard too. Tried front ports, back ports, usb 2, usb 3, usb root power settings in device manager, nothing would stop it. Reseated everything, including usb headers, nada.
So I'm like fuck do I need a humidifier, is this normal? Nope, hooked up my old PC back to the same setup, I can straight up rub my ass around on my couch and zap the mouse good, it doesn't even flinch. Leaning towards some sort of motherboard grounding issue, and thats prob what fried the first GPU in the first place right?
Long story long, I just got off the phone with support and theyre gonna rma it again and replacr the motherboard and test it a bunch.
Tldr: if even the tiniest static discharge near your computer is making your usb ports lose connection, that shouldnt be happening and you should rma.