Almost certainly yes, two sticks >>>> four sticks.
There are some motherboards where it does not matter. This is described as "Daisychain" vs "T Topology". Buildzoid will comment extensively on this when looking at a motherboard's pics in his youtube vids. Almost every X570 is a daisychain layout, the better overclocking design and the one that prefers two sticks.
It's like this crap attempt at a diagram:
Code:
Daisychain:
/-- Memory controller ---> DIMM A1 ---> DIMM A2
CPU <
\-- Memory controller ---> DIMM B1 ---> DIMM B2
T-Topology:
/--> DIMM A1
/-- Memory controller -|
/ \--> DIMM A2
CPU <
\ /--> DIMM B1
\-- Memory controller -|
\--> DIMM B2
The shorter trace lengths in daisychain are better for overclocking, but get worse when 4 slots are filled. The longer more complex traces for T-topology work better when all are full, but have a lower ceiling.
If you're not pushing high clocks it doesn't matter a huge amount now I should imagine, though I don't know. On older 1xxx especially and perhaps 2xxx Ryzens, a daisychain motherboard might be as extreme as allowing 3200 CL14 1T at two sticks, but having to back off to 2400 2T for all four. It is nowhere near that bad on a 3xxx I am sure - but you're still going to need to back off at least a little somewhere (if daisychain).
I am no expert in this, the above might have many errors! I have watched a lot of Buildzoid though lol.
