I generally only play through these types of games once and I'm nearing where you would choose. I know the general nature of the paths from the wiki. I also generally don't go for the optional extra hard bosses but Purification ending seems good. But the idea of an extra-hard Hirata Estate with Omega Owl seems like it could be tedious. I'm definitely not going to do Shura because I'm a good boy. And Dragon's Homecoming seems weird because it appears very separate from the main thrust of the game.