I don't see anything that stands out as being a huge failure like Fallout 76 this past year yet.
I'm not into the type of game, but what I have seen of Anthem looks solid. I don't know how they are going to handle the mtx around the game, that is what would worry me the most.
Crackdown 3 is the game I'd be worried about most. So many delays and we still haven't seen much in terms of change from what was initially announced eons ago.
Days Gone is something that won't be to my taste I think, but it will do well commercially and it will at least do fine critically (75+).
Fire Emblem: Three Houses is something I'm mildly worried about from Nintendo. Intelligent Systems has been a bit more hit and miss lately than they normally have been between the shaky Paper Mario entries, the divisive Fire Emblem Fates, and the commercial bomb of Codename STEAM. Anything else from Nintendo I think will be delayed or not shown until they are in fine form, this goes for Metroid Prime 4, Animal Crossing, Pokemon, Luigi's Mansion, Town, Bayonetta 3, etc.
Shenmue 3 is a good contender for me though. Kingdom Hearts 3 may not be a game worthy of a 14 year gap in mainline entries.