It's so hard to know for sure. Some of my extended family on places like FB which I only use for direct family and very close friends, have become insufferable in their pro-Trump discussions. Starting discussions from a very sided perspective which I have no desire to engage. And yet, they're family and outside of this political discussion I love them very much and prior to 2016 never had a single beef with them.
So it's hard to say I'd ever permanently write them off and not want to have anything to do with them... but it's crossed my mind multiple times. If I knew we could still all get together and NOT talk about it, I'd really have no problem. I'm not saying that I would in any way accept their beliefs, but I'm not to the point where I'd disown them because of it. Now if they actively did things like were involved in violent protests, etc., that would def change my mind I think. Luckily that's not been the case (that I'm aware of).