Here's the laundry list:
1. Controls
2. Linear story missions
Controls + story missions is basically something you're dealing with the entire experience and those themselves contain a laundry list of issues within them.
3. Wanted system/AI aggression.
4. Arthur glitching around in a 2 metre radius 50% of the time you try to interact with something.
5. Poor menus/sub menus for inventory management.
6. Impossible to find collectibles.
7. A weapon loadout system that doesn't save properly.
8. Weather that lasts 20 seconds before it stops completely.
9. Day/night cycle too fast especially when you have time specific missions.
10. Lame fast travel.
11. Cores add nothing but annoyance and UI clutter.
12. Zero economy balance.
13. Mission replay system is garbage and makes trying to 3 star them a miserable experience.
I can go on. Also RDR 2 is my GOTY.
The difference in a lot of the big games is still 30 vs 60 on PC a lot of the time, or lower resolution. It's probably also more noticeable in an action game like God of War compared to RDR2 with it's much slower pacing.
If anything 30fps in RDR 2 is more noticeable to me because the controls are already laggy as hell and the added input latency from the frame rate exacerbates everything. A 60fps PC version will likely make a massive difference. The Witcher 3 was the same - the console version controls are horrendous but it's much more tolerable on PC.