Just want to add my two-cents:
It's worth noting that the artist who gave this presentation, Alessandro Taini, hasn't been at Ninja Theory in nearly ten years (he left shortly after this presentation). After DmC, Ninja Theory has since become a studio that's made games with positive female and queer representation (Hellblade and Bleeding Edge in particular) since Taini departed. Also, they're one of the top devs out there who have been putting a lot of great work portraying an empathetic view of mental health in games. So I do take issue with folks trying to insinuate that NT is a studio run by bigots because of a dumb, insensitive joke made during one of the former artists at a GDC panel. I attended this panel at GDC 2013 while at my old job, and people largely dismissed the joke itself as cheap humor. I don't think it was intended to be a vicious homophobic attack that some people are trying to make it out to be in the years since it's been brought out again.
Now, I'm not this saying to dismiss feelings of disgust with the joke he made. If you feel offended by the joke, then that's totally valid, and you have the right to feel that way. I absolutely believe that humor should not go for crass, dumb jokes at the expense of others for cheap laughs. Still, I do get the impression from this thread that people are looking at this more to just have another reason to hate on Ninja Theory's work on DmC, which is still such a lightning rod of hate more than ten years on. Also, the mainline DMC series has its own bad actor that the fanbase doesn't really talk much about since they finally got DMC5. Ninja Theory will never make another Devil May Cry game or even work with Capcom again. Yet, Reuben Langdon--a transphobe, holocaust denier, and anti-Me Too/BLM conspiracy theorist--is still working with Capcom on new games. If you truly feel that something must down to root out toxic elements, I encourage to look at the negative elements currently attached to the things you love.