If you want to get more performance your first options should be
Screen Space Reflections and
Volumetric Lights. As in many modern games, especially Quantum Break, those settings cost and could gain huge performance steps.
If you have a GTX 1070 and aim for 1080p at 60FPS you should set at least one of those to medium, preferable Volumetric Lights since the difference is smaller than going from SSR high to medium. If you aim for 1440p at 30fps (GTX 1070) you could leave both at high since fps are around 45 with both on medium.
MSAA comes with a very small performance hit (I have MFAA activated in the NVCP), around 3-5%, so I would leave it on 2x.
Here are comparison screenshots:
Everything maxed out, 2xMSAA, no RTX, 1080p
Volumetric lights on medium, rest maxed out, 2xMSAA, no RTX, 1080p
As above but Screen Space Reflections on medium
Everything maxed out, 1440p internal, 2xMSAA
Volumetric lights and SSR on medium, 2xMSAA, 2160p internal
System: i5 4690k, GTX 1070 (slight OC, Clock and RAM speed +180Mhz), 16GB DDR3 RAM. Installed on SSD.