Mass Effect is both one of the most magical game universes out there and also one of the most tainted. I don't envy them trying to make a new one.
What made Mass Effect great was equal parts story and worldbuilding, and the discovery inherent in that first game, the imagination that went into the universe, was palpable, and it carried them through three games where the story got increasingly worse (note, only the story, the writing in 2 especially is fucking amazing, but the plot goes NOWHERE), but by the end of the series it felt 'done' - they need to make a new game that has that same imagination and discovery, but they are too afraid to distance anything from the lore of the games that came before, which makes it an impossible task.
Andromeda tried, by getting away from the Milky way, but then made like, ONE new race and otherwise just tacked on all the same bullshit we've seen for 3 games already - what was the point? Even if the story had been good (it was serviceable), the actual world feels v ery same old.
Game can never pl,ease everyone, some people want what I want,. which is to recapture that wonder of the original trilogy, and others want to be blanketed in the lore they already invested in, and you can't have both.
It's basically the star wars problem.