If you lack the fundamental understanding that this is a class struggle, you are unable to process information like the one posted on the OP.
Do you think that people are fundamentally unable to change? Then you have a worldview that have not gone past the 1700's, and even then, changes in personality and behiour was an everyday occurence (of course it was).
[A certain group of people is beyond saving] is exactly the slogen that was used to justify slavery, nationalistic regimes attacking others without agression from the other side, it has fueled countless genocides through history.
To pull this back to the context of Mississipi: if you consider yourself a "progressive" and also happens to think that a whole state should either be ignored (or worse), you are not dealing with the problem in any practical sense of the word. Bernie, for example, champions programs that would help the working class. That would mean helping the racist part of the working class too. And that is okay.
If you think that it is not okay, universal programs are no longer things that you think are worth striving for. Universal healthcare? Firefighters coming to you when your house is on fire? Free education? These are programs that help everyone in the country.
You cannot look at this through the state of race alone(!), and even if you do, you need to do a serious amount of mental gymnastics to ignore the fact that the powerful and elite class have, have enacted racist policies again and again that disproportionally hurt blacks because they were the most vulnerable economically and socially. Dismantling the social gap between the powerful and the working class is something that is in the best interest of anyone who is not part of the elite or the managerial class, regardless of what outdated, harmful, and outright criminal views they might have of each other.
The alternative is: ignoring many states, taking losses and keeping up the divide and conquer that plays to the hands of the elite. And that is exactly what was tried in 2016, and it gave the US Trump.