If your friends or family aren't taking things seriously or embraces actions and rhetoric that places the economy over mitigating risk to people... then I'd say cut them out of your life if you can. At the bare minimum don't hang out with them.
Me personally? We have friends and family in more conservative counties that either have more spread, or haven't been testing that much meaning lower reported numbers and more people waving snek flags and piling into bars, restaurants, etc.. So I don't know when we'll be seeing them since some are older and gave ongoing health issues.
Even though my partner and I feel fine, healthy, and taking precautions to mitigate the exposure, we want to make sure the risk to friends and family is being managed smartly where they live before considering visiting in person.